1Division of Veterinary Pathology, F.V.Sc &A.H., SKUAST-J, R.S.Pura;
2Madras Veterinary College, Chennai.
3Department of Pathology, Veterinary College and Research Institute Namakkal, Tamil Nadu
*Part of M.V.Sc thesis submitted to Tamil Nadu Veterinary and Animal Sciences University, Chennai by the first authour;
Clinico-pathological effects of citrinin (CIT), a nephrotoxin and aflatoxin B1 (AFB1), a hepatotoxin were studied in broiler chicken by giving my cotoxins free feed to group A, 150.0 ppm of CIT to group B, 0.5 ppm of AFB1 to group C and combination of these two mycotoxins to group D. The body weight was very poorly pronounced in CIT fed group birds compared with other group birds. A significant decreased feed intake was recorded in CIT (group B) and CIT with AFB1 combined toxins (group D) fed birds compared with other groups. AFB1 alone (group C) and combined toxins (group D) fed birds showed a significant decrease in haematological and serum biochemical values. Significant enlargement of kidneys in group B and hepatomegaly in group C and D was recorded when compared with that in controls. However, in combined toxins fed birds (group D), additive or synergistic effect of these two toxins was not much appreciated.
Aflatoxin Bj, Broiler chicken, Citrinin, Clinico-pathological study, Interaction
