An outbreak of classical swine fever (CSF) in Jammu region (India): A pathomorphological study

An outbreak of classical swine fever (CSF) in three adjoining commercial pig farms in Gadigarh, R.S.Pura of Jammu region occurred. At necropsy, blotching of skin of ears, snout and ventral abdomen, and muco-conjunctivitis were noticed externally. Vascular lesions (congestion and haemorrhages) were seen in lymphoid organs (lymph node, spleen and tonsils), liver, kidneys, heart, stomach, intestinal mucosa, brain and reproductive organs (testes, ovaries and non-pregnant uterus). Splenic infarcts and presence of appreciable amount of thin, serous fluid in peritoneal and pericardial cavities were observed. On histopathological examination, widespread vascular changes (congestion/haemorrhages) with occasional endothelial cell swelling, variable degree of lymphoid depletion in lymph nodes, spleen, thymus, Peyer's patches and tonsils; hepatocytic degeneration, acute nephritis, acute bronchopneumonia and degeneration of spermatogonial cells in seminiferous tubules of testes were prominently seen.