Ameloblastic fibrosarcoma in a cow

A 6-year old Gir crossbred cow was presented for the evaluation of an anterior mandibular-gingival mass. On clinical examination, a firm solid mass of growth was found on the anterior part of the mandible. The tumour mass was composed of numerous islands of odontogenic epithelium enclosed in a loose connective tissue matrix. The odontogenic epithelia were separated by a stroma which showed hyper- cellularity with plump fibroblast like cells showing a moderate degree of nuclear pleomorphism. The cells revealed occasional mitotic activity. Ameloblastic fibrosarcoma was diagnosed by histopathological examination of biopsy specimen. The animal was given a poor prognosis due to the malignant nature of the tumour.