Haemato-biochemical changes in canine parvoviral infection

Fifteen cases of canine parvovirus (CPV) were diagnosed during the study by a dot-ELISA kit. The most common clinical signs observed in current investigation were nasal and ocular discharges, depression, anorexia, vomiting and diarrhoea. Data of haematology and serum biochemistry, was compared with the reference data. The frequent hematological abnormalities observed were microcytic hypochromic non-regenerative anemia, lymphopenia, sometimes associated with either leukopenia or leukocytosis often showing shift to left and thrombocytopenia. The levels of blood urea nitrogen (BUN), creatinine, alkaline phosphatase (ALP) and alanine amino transferase (ALT) were elevated while the total protein (TP) and albumin levels were decreased.