Spontaneous cutaneous hemangiosarcoma in mice

Two cases of spontaneous cutaneous hemangiosarcoma in Swiss mice are reported. Two terminal breeder female mice were presented with the history of subcutaneous swelling and ulceration of skin with or without necrosis. The tumour masses were recovered and examined for gross and histopathological alterations. Histopathological features were consistent with hemangiosarcoma. No evidence of metastasis was found in visceral organs.