Isolation of Aspergillus versicolor from fungal contaminated meadow grass and its toxicopathological study in Wistar albino rats

Fungal infected meadow grass, consumed by the cattle suffered from mycotoxicosis was subjected to fungal isolation. The fungus was identified as Aspergillus versicolor. Sub-acute toxicity study of the culture filtrate of A. versicolor was carried out in Wistar albino rats. The animals were gavaged with culture filtrate at the dose rate of 0.5,1 and 2 ml/100g daily for 28 days. There was a significant (p<0.001) increase in the serum ALT and AST. There was a significant (p<0.001) decrease in haematological parameters such as TEC, Hb and PCV. It was concluded that the present study indicated the toxic features of the culture filtrates of A. versicolor, isolated fungi from infected meadow grass in rats.