A case report of ovarian haemangiosarcoma in a dog

The present study report a case of primary ovarian haemagiosarcoma in a ten years old non-descript female dog presented for the treatment of pyometra. Haemato-biochemical analysis revealed anaemia, leucocytosis due to neutrophilia and increased blood urea nitrogen. Radiograph and ultrasonography of abdominal region revealed distended uterine horns with enlarged left ovary and no metastasis were observed. Ovariohysterectomy was done and on gross examination, the ovary appeared tennis ball-like, reddish in colour, firm in consistency and cut sections showed multi-lobulated chambers filled with blood clot. Histopathological examination revealed variable sized incomplete vascular channels filled with variable amount of erythrocytes and interspersed by fibrous connective tissue stroma. At places, these channels were composed of pleomorphic immature neoplastic endothelial cells with spindle to ovoid hyperchromatic nuclei and indistinct cytoplasm. Only a few mitotic figures were observed. It also revealed haemorrhages, haemosiderin laden macrophages and focal areas of necrosis with leucocytic infiltration. Broad ligament and uterine wall were normal. Adjacent peritoneum did not reveal haemorrhages and secondary nodules. Based on gross and histopathological findings, it was diagnosed as primary ovarian haemangiosarcoma.