1Division of Pathology, ICAR-Indian Veterinary Research Institute, Izatnagar-243122, Uttar Pradesh, India
2Division of Surgery, ICAR-Indian Veterinary Research Institute, Izatnagar-243122, Uttar Pradesh, India
*Address for Correspondence S.K. Maiti, Division of Surgery, ICAR-Indian Veterinary Research Institute, Izatnagar-243122, Uttar Pradesh, India, e-mail: swapanivri@gmail.com
The liver is an organ that plays a central role in maintaining metabolic homeostasis, in its functions of metabolism, synthesis and storage of nutrients. This study was conducted to evaluate the biochemical changes following partial hepatectomy in wistar rats. A total of twenty animals were subjected to partial hepatectomy under general anaesthesia and then were used to determine the changes in liver parenchymal enzymes like ALP, AST, ALT, yGT, total protein, albumin, bilirubin and blood glucose at various time intervals for a period of 40 days. The results were compared with normal values of animals prior to surgery. It was observed that after partial hepatectomy the levels of ALP, AST, ALT, yGT, bilirubin increased while the level of blood glucose, total protein and albumin level decreased.
How to cite this article: Mohan, D., Maiti, S.K., Shivaraju, S., Kalaiselvan, E, Raghuvanshi, P.D.S., Kumar, N. and Singh, K.P. (2019). Biochemical profile following partial hepatectomy in Wistar rats. Indian J. Vet. Pathol., 43(2): 144–146.
Biochemical changes, Partial hepatectomy, Rat
