1Central Agricultural University, Jalukie, Nagaland, India
2Department of Veterinary Pathology, Central Agricultural University, Selesih, Mizoram, India;
*Address for Correspondence Dr. R. Ravindran, Department of Veterinary Pathology, Central Agricultural University, Selesih, Mizoram, India, e-mail: ravindranvet@gmail.com
A total of 16 dogs died during August 2017 to May 2018 in Aizawl district of Mizoram, India, of which, 2 carcasses were necropsied in order to study the gross pathological changes, histopathology and molecular diagnosis of canine distemper virus. The major gross changes observed were haemorrhages and pneumonia in lungs, hepatomegaly, spleenomegaly and haemorrhagic areas of intenstine. Interstitial pneumonia in lungs and syncytia formation of intestine were observed histopathologically. Reverse transcription polymerase chain reaction (RT-PCR) was performed to detect the specific gene fragments of canine distemper virus, which resulted in amplification of 480 bp region of N gene and confirmed the diagnosis of CDV.
How to cite this article: Lalrinkima, Ravindran, R., Rajkhowa, T.K., Singh, Y.D., Arya, R.S., Lalruatkima, A. Pathology and molecular diagnosis of canine distemper virus in Aizawl, Mizoram. (2019). Indian J. Vet. Pathol., 43(3): 231–233.
Canine distemper virus, Histopathology, Molecular diagnosis, Polymerase chain reaction, Reverse transcription
