A case of canine transitional cell carcinoma

Transitional Cell carcinoma (TCC) accounts for less than 2% of all the cancer diagnosis in canine practice. A 3.5 years old male Dachshund dog was presented to department of Veterinary Surgery and Radiology, Veterinary College, Hassan with a history of anorexia, dysuria, distended abdomen, restlessness, arching of body while urinating and haematuria. On physical examination, prepuce was swollen with bite wounds on penis, distended abdomen, dribbling of urine and pyrexia. Radiography revealed distended bladder and radio opaque mass in urethra. A small tumor mass adherent to ventral surface of floor of bladder was excised surgically and cystoliths were removed manually. Histopathological examination revealed large epithelial cells with multiple cellular and nuclear features of atypia forming papillary structures. In addition, neoplastic cells also showed abundant eosinophilic cytoplasm with large nucleus. Melamed-Wolinska bodies characteristic of these type of neoplasm representing large vacuoles containing stippled eosinophilic materials were observed.Thus, a case of Transitional Cell Carcinoma (TCC) was diagnosed in a male Dachshund dog.