1Division of Pathology, ICAR-Indian Veterinary Research Institute, Izatnagar, U.P.-243 122
2ICAR-DFMD-International Centre for Foot and Mouth Disease, Arugul, Jatni, Odisha-752 050
*Address for Correspondence, Dr Monalisa Sahoo, ICAR-DFMD-International Centre for Foot and Mouth Disease, Arugul, Jatni, Odisha-752 050, E-mail: vety.lisa@gmail.com
**Address for Correspondence, Dr Rajendra Singh, Division of Pathology, ICAR-Indian Veterinary Research Institute, Izatnagar, U.P.-243 122
Online Published on 07 December, 2022.
A total of 250 brain, collected mostly from routine slaughter and some fallen pigs, showed gross lesions of neurocysticercosis (6 cases), hemorrhages (2 cases), and focal malacia (1 case), and microscopic lesions in inflammatory lesions (43 cases). Among the inflammatory lesions, perivascular cuffings topped the list. The mononuclear cuffs around the vessels in 22 cases including 4 cases with mix of eosinophils indicated possible involvement of bacteria/virus/parasite. In addition, meningitis / meningoencephalitis (11 cases), demyelination, microabscess, chorioditis and neuronal loss in Purkinje and granule cell layer were also noticed. A good number of cases (10.8%) were associated with vascular engorgement/hemorrhages/vasogenic oedema and in few cases with gliosis and PVC. In 20 cases (8%), glial cell reaction was evident in the form of microgliosis, satellitosis, astrogliosis, subependymal gliosis and oligodendrogliosis, indicating perturbation of brain parenchyma. Among parasitic affections, Cysticercus cellulosae cysts (8 cases) and sarcocysts (6 cases) were also recorded. A total of 35 cases showing microscopic lesions of meningitis and meningoencephalitis were screened for S. suis by PCR and of which, 4 turned out positive for the same.
Brain, Histopathology, PCR, Pigs, Slaughtered pigs, Spontaneous lesions, S. suis
