Department of Pathology, Mumbai Veterinary College, Parel, Mumbai, Maharashtra Animal and Fishery Sciences University, Nagpur
*Address for Correspondence, Dr G.K. Sawale, Assistant Professor, Department of Pathology, MVC, Mumbai, E-mail: ganeshsawale@mafsu.in
Online Published on 31 October, 2023.
The study was conducted to know the occurrence of canine hypothyroidism in dogs of Mumbai region. Total of twenty five cases were considered for this study based on the clinical signs and serum hormone profile (T3, T4 and TSH). The study revealed highest incidence of hypothyroidism in the age group of 5-10 years (64%) followed by 1 to 5 years (28%) and lowest in age group of more than 10 years (8%). The incidence was more in male (64%) than female (36%) dogs. Breed wise, highest incidence was observed in Labradors (36%) and non-descript breeds (32%) followed by Golden retriever (12%) and German shepherd (8%). The clinical symptoms of hypothyroidism were categorized in to dermatological (96.00%) and metabolic (52%) disorders. In metabolic disorders (84%), particularly lethargy (76%), obesity or weight gain (44%) and exercise intolerance (24%) were observed. Dermatological abnormalities included alopecia (80%), poor coat quality (30%), rat tail appearance (12%) and hyperpigmentation (20%). On the basis of thyroid profile by ECLIA method, all 25 cases were found with low T4 and T3, whereas TSH values were found within the normal and subnormal range. The pathomorphological changes observed in the skin comprised of hyperkeratosis and abnormal thinning of epidermis. All hair follicles were in telogen phase with marked hyperkeratosis of the external root, and focal subepidermal edema was observed. In some cases, in which secondary bacterial infection was observed showed acanthosis with infiltration of polymorphonuclear cells.
Diagnosis, Dog, Hormone, Hypothyroidism, Pathology, T3, T4, TSH
