Indian Journal of Veterinary Pathology

Hexavalent chromium is a potent toxic agent found to be carcinogenic in human and animals. An experiment was conducted for a period of four months with 120 female wistar rats. These were maintained under standard management conditions with feed and water ad libitum throughout the experiment. These rats were divided into six groups. Group I was provided with routine basal diet. Group II with potassium dichromate @ 500 ppm, whereas group III was supplemented with vitamin C @ 100 mg/kg body weight. Group IV was provided with Emblica officinalis powder @ 2% in feed, group V and VI was provided with ameliorative diets. A detailed necropsy was conducted and organs like uterus, fallopian tube and ovaries were collected for ultra structural studies. The investigation revealed that there is a great damage to cellular and sub cellular structures in toxin group (II) where as a distinct amelioration is observed in ameliorative groups.