1School of Biology, Indian Institute of Science Education and Research-Thiruvananthapuram, Maruthamala PO, Vithura, Thirunvananthapuram-695551
2Research Scientist, Health Economics and Finance Research Group, Research Institute of Medical and Health Sciences, University of Sharjah, Sharjah, UAE e-mail: rnair@sharjah.ac.ae
Division of Experimental Pathology, Biomedical Technology Wing, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Poojappura695012, India
*Address of correspondence Dr. Chandramohanan Purnima; E-mail: purnimac@iisertvm.ac.in
Collagen-rich extracellular matrices (ECMs) recovered from mammalian organs and tissue have found clinical uses in several formats like thin sheets, powder, ointments, gels, etc.; either as a standalone tissue engineering scaffold or in combination with other biomaterials and pharmaceuticals for many regenerative medical applications. Out of these, gel formulations of ‘advanced wound care products’ made of animal-derived ECMs have high utility because of structural adaptability, biocompatibility, and tunable physicochemical properties. This study demostrated the wound healing potential of a porcine cholecystic extracellular matrix gel formulation in rat full-thickness skin-excision wound model by gross and histomorphological studies.
Extracellular matrix, Full-thickness skin excision wound, Wound healing
