1Processing and Product Development Division, Indian Institute of Natural Resins & Gums, Namkum, Ranchi – 834010 (Jharkhand); E-mail: mzs_2009@rediffmail.com
2Department of Pharmaceutical Sciences, BIT Mesra, Ranchi-835215 (Jharkhand)
Online published on 25 September, 2012.
The present study was undertaken to assess the anti-inflammatory activity of the resinoids of Boswellia serrata in inbred Wistar rats. Exudates of Boswellia serrata were collected from four different States of India i.e. Andhra Pradesh, Chhattisgarh, Gujarat and Madhya Pradesh and their resinoids prepared in two solvents i.e. ethylacetate (moderately non-polar) and ethyl alcohol (highly polar). Physico-chemical characterization of these resinoids was carried out to determine their appearance, yield %, moisture %, ash %, acid value (mg/KOH/g), saponification value (mg/KOH/g), ester value and iodine value (g/g). The ethylacetate resinoids of Boswellia serrata from Andhra Pradesh (C1) & Madhya Pradesh (C3) as also Commiphora mukul (C7) from Madhya Pradesh showed significant anti-inflammatory activities as compared with the control group, even better than that of the standard drug Shallaki, in rats. The resinoids of Boswellia serrata and Commiphora mukul which showed significant anti-inflammatory activity have low acid value and no ash content.
Anti-inflammatory activity, Boswellia serrata, Frankincense, Resinoids Salai
