Indian Journal of Veterinary Research (The)

  • Year: 2023
  • Volume: 32
  • Issue: 2

Serotypes Protective Immune Response of Pasteurella multocida A:1 Phage Lysate Vaccine in Murine Model

  • Author:
  • Anshuja Nagdive1, Poonam Kumari1, Mayank Rawat1,*, Ashok Kumar Tiwari1, Somanath Chavhan2
  • Total Page Count: 4
  • Published Online: Sep 27, 2024
  • Page Number: 11 to 14

1Division of Biological Standardization, ICAR-Indian Veterinary Research Institute, Izatnagar-243122 (Uttar Pradesh)

2Livestock Development Officer, VD-1, Anturli, Tal- Muktainagar, Dist-Jalgaon-425306 (M.S.)

Abstract

Fowl cholera (FC) is caused by serogroup A (A:1, A:3, A:4) serotypes of Pasteurella multocida (P. multocida). The killed whole cell preparations of accepted strains are not known to induce an across serotype response and live vaccines are not safe. Thus, an antigenic preparation that can induce a cross protective response is desired. The trials of P. multocida A:1 phage lysate in mice have shown homologous and heterologous response against stringent virulent challenge with P. multocida A:1, A:3, A:4 giving completes across serotype protection.

Keywords

Bacteriophage lysate, Fowl cholera, Immune response, P. multocida