Indian Journal of Veterinary Surgery
  • Year: 1998
  • Volume: 19
  • Issue: 1

Reversal of cardiopulmonary effects of epidural xylazine and detomidine by atipamezole or yohimbine in buffaloes (Bubalus bubalis)

  • Author:
  • S.K. Tiwari1, Amresh Kumar2
  • Total Page Count: 4
  • Page Number: 16 to 19

1Dept. of Surgery and Rediology, College of Vet. Sci. Durg. (M.P.)

2Dept. of Surgery & Radiology, College of Vet. Sci. and Dean Student Welfare

G.B. Pant University of Agriculture and Technology, Pantnagar-263 145 (U.P.)

Abstract

Epidural administration of xylazine (a)0 JO mg/kg or detomidine @ 50 fig/kg in 20 healthy male buffalo calves caused significant (P<0.01) increase followed by decrease in mean arterial blood pressure, significant (P<0 01) increase m central venous pressure, decrease in tidal and minute volumes (P<0 01), bradycardia, increase in PR and OT intervals and incomplete atrw-ventricular block Intravenous administration of atipamezole %10 uglkg or yohimbine (aj 0.125 mg/kg, 15 minutes post-injection caused effective reversal with MAP and CVP reaching near preadministration level within 10 to 30 minutes, significant (P<0 05) increase in tidal and minute volumes, tachycardia and abolition of atrioventricular block Atipamezole induced reversal was, however, more rapid, effective and complete in comparison to yohimbine

Keywords

Atipamezole, Buffalo, Detomidine, Epidural analgesia, Xylazine, Yohimbine