Production of an animal model of posttraumatic osteomyelitis

The experiment was conducted in 36 goats divided into 6 equal groups. Osteomyelitis was successfully produced by using unsterilized Steinmann pin, K-nail and Stainless steel plate in femoral fracture in groups A -1, B-l and C-l, respectively, by 30 days after operation. Groups A -2, B-2 and C-2 served as corresponding controls where sterilized devices-were-used. The predominant clinical signs were pain, lameness and pyrexia. Radiographically tissue swelling bony lysis around the fixation devices, periosteal reaction and cortical lysis were evident. Cultural examination yielded S. aureus as a common isolate.