Complications of manganese chloride used in buffaloes subjected to diaphragmatic herniorrhaphy

The present study was aimed to evaluate the anti-oxidant property of manganese chloride in buffaloes subjected to diaphragmatic herniorrhaphy. Clinical and oxidative stress parameters were studied and comparison was made with the base values of affected treated and index values from healthy farm buffaloes. Based on this study it was concluded that infusion of manganese chloride 10 mg/kg/h in 1 L dextrose saline intravenously in buffaloes prior to diaphragmatic herniorrhaphy, though improves tissue perfusion, causes prolonged tachycardia that may lead to mortality. All the animals showed the signs of restlessness, excessive lacrimation, salivation, and tachycardia and ultimately did not recover after surgery. Hence, further experimentation with lower doses of managanese chloride are required to establish safer use of this salt.