Haematological and biochemical changes associated with traumatic posterior paralysis and spinal fixation in dogs

Eighteen dogs with traumatic posterior paralysis presented to the college hospital were treated by spinal fixation with or without hemilaminectomy or non-surgical method (Groups A, B and C, respectively of six dogs each). They were subjected to haematological and biochemical evaluation on 0, 15th, 30th, 45th and 60th days. The mean Hb, PCV, TEC, and serum calcium, phosphorus, potassium, aspartate aminotransferase and alanine aminotransferase values were within the normal range in all dogs. TLC values, which were raised in all dogs 0 and 15th day, fell to normal levels by 30th day in Groups A and B, whereas in Group C the values increased till the 60th day. Even though there was no statistically significant difference (P<0.05) between the dogs of Groups A and B in the neutrophil and lymphocyte counts, a statistically significant variation (P<0.05) in these values were observed between dogs of these groups and those of Group C on the 45th and 60th days. Mean serum alkaline phosphatase values were above the normal range and showed statistically significant (P<0.05) difference between dogs of the three groups on day 0. However, in Groups A and B the values lowered non-significantly after the 30th post-operative day, whereas in Group C the values increased non-significantly till the 60^th day.