The study was undertaken to evaluate the haemodynamic and electrocardiographic changes following spinal administration of combinations of ketamine with bupivacaine, xylazine or buprenorphine in buffalo calves. Eighteen buffalo calves were used in three equal groups A, B and C. The combinations of ketamine (2.5 mg/kg b.wt.) with bupivacaine (0.25 mg/kg b.wt.) were administered spinally at lumbosacral space in group A, B and C, respectively. The MAP, CVP and ECG were recorded at different intervals up to 180 min of drugs injection.
The results indicated least alterations in haemodynamic and ECG parameters after spinal administration of bupivacaine and ketamine combination, as compared to others. Combination of buprenorphine and ketamine produced irregular ECG pattern.
Buffalo calves, Buprenorphine, Buprivacaine, ECG, Haemodynamic charges, Ketamine, Spinal analgesia, Xylazine