1Faculty of Veterinary Medicine, Universiti Putra Malaysia, 43400, UPM, Serdang, Malaysia.
2Faculty of Medicine, University, Malaysia.
*Corresponding author: E-mail: vsr_jo@yahoo.co.in
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This study was focused to evaluate the efficacy of poultry feather keratin and basic fibroblast growth factors (bFGF) with gelatine composite film on wound healing. The study was conducted in 18 mongrel dogs divided into 3 groups of 6 animals each. In group I, experimentally created open wound was treated with Gentamicin ointment. Group II and III animals were treated with keratin-gelatin film and bFGF-gelatin film, respectively after soaking for 1–2 min in Getamicin. Wound healing was evaluated histopathologically based on fibroblast formation, angiogenesis and collagen formation on days 4, 8, 12, 16 and 20 postoperatively. The results of the study revealed that keratin-gelatin composite film treated wounds showed early angiogenesis and better collagen formation.
bFGF, Dog, Keratin, Wound healing
