Indian Journal of Veterinary Surgery

  • Year: 2009
  • Volume: 30
  • Issue: 1

Comparative evaluation of CO2 and iopromide as contrast agents for renal angiography in dogs

  • Author:
  • G.U. Rane1,2, P.V. Parikh1,2, M.M. Rajapurkar1,3, D.B. Patil1,2,, N.H. Kelawala1,2, S.S. Patel1,2, P.B. Patil1,4
  • Total Page Count: 4
  • DOI:
  • Page Number: 5 to 8

1Anand Agricultural University, Anand-388 001 (Gujarat).

2Dept. of Surgery and Radiology, Veterinary College, AAU, Anand.

3Dept. of Nephrology, Muljibhai Patel Urological Hospital (MPUH).

4Jayaramadas Patel Academic Center, MPUH.

*Corresponding author, E-mail: db1608@gmail.com

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Abstract

The aim of this study was to compare the renal injury and the quality of images of iodinated contrast (iopromide) and CO2 using digital subtraction angiography in dogs. 17 dogs were randomly assigned to receive iodinated contrast (iopromide n=5) or CO2 (n=12) using 6F pigtail catheter, which was introduced via femoral approach to perform aortogram. Serum creatinine (S.Cr.) and urinary enzymes such as N-acetyl-β-D-glucosaminidase (NAG), alanine aminopeptidase (AAP), gamma glutamyl transferase (GGT) were measured before and 0 and 48 hr after DSA to assess renal injury. PaCO2 was measured before and immediately after the procedure. There was no change in S.Cr. in both groups; however, significantly more enzymuria was seen in iodinated contrast. Images obtained with iodinated contrast agents were superior to those with CO2. However, CO2 is good alternative contrast agent in high risk individuals to reduce the risk of renal injury and quality of images is able to delineate the aorta and main renal artery.

Keywords

Contrast Nephropathy, CO2 angiogram, Dog, Enzymuria