Indian Journal of Veterinary Surgery
  • Year: 2009
  • Volume: 30
  • Issue: 1

Comparison of neurological recovery facilitated by a cox-2 inhibitor as well as long acting prednisolone in paraplegic rabbits

  • Author:
  • A. Gopinathan1,2, A.M. Pawde1,3,, Amarpal 1,3, H.P. Aithal1,3, P. Kinjavdekar1,3, A.K. Sharma1,4, K. Singh1,2
  • Total Page Count: 5
  • Page Number: 17 to 21

1Indian Veterinary Research Institute, Izatnagar (UP).

2Veterinary College, GADVASU, Ludhiana.

3Division of Surgery.

4Division of Pathology.

*Corresponding author: E.mail: apawde@ivri.up.nic.in

Abstract

Neurological recovery facilitated by a meloxicam, and methyl prednisolone acetate was compared with that of methyl prednisolone sodium succinate in a model of acute spinal cord trauma in 12 New Zealand White rabbits. The results were evaluated return of motor function clinical, hematological, biochemical and histopathological changes in the spinal cord. Rabbits treated with meloxicam had a better neurological recovery compared to the steroid groups. Comparison of the different indicators of stress also revealed that meloxicam was better to block secondary changes to spinal cord trauma.

Keywords

Cox-2 inhibitor, Paraplegia, Prednisolone, Rabbits