Less-invasive hysterocystoplasty technique: experimental study in goats

A novel less-invasive hysterocystoplasty technique was evaluated experimentally in goats, via closure of a large defect of the dorsal aspect of the bladder by the uterus. Follow up for six months included radiographic and ultrasonographic examinations, evaluation of kidney function and electrolyte changes, and histological examinations. Microscopically the perimetrium was completely covered with healthy urothelium under which disorganized smooth muscle fibers appeared admixed with slight fibrosis, without demonstrable evidences of shrinkage, infection or malignant transformation. Generally, the technique had many advantages as it required less-invasive procedures, avoided intestinal resection, achieved high survival rate without life threatening complications, caused no significant changes in kidney function or electrolyte levels, and associated with proper healing, acceptable degree of fibrosis, and absence of shrinkage or metaplasia. The technique can be considered as an alternative cystoplasty technique.