Ketofol as a general anaesthetic agent in diazepam or midazolam premedicated and halothane anaesthetized dogs

Twelve dogs divided into two groups were given atropine sulphate (0.04 mg/kg, s.c.) and butorphanol (0.2 mg/kg, i.m.). After 10 min the animals of group I were pre-medicated with diazepam (0.5 mg/kg, i.v.) and animals of group II with midazolam (0.5 mg/kg, i.v.). Inj. ketofol (ketamine and propofol mixture 1: 1) was used to induce general anaesthesia in all the animals and were maintained on halothane throughout the surgical procedure. Induction dose of ketofol utilized was 3.0 mg/kg b.wt in both groups. Ketofol (ketamine and propofol mixed in single syringe-3 mg/kg each) is an excellent induction agent for general anaesthesia in both diazepam and midazolam premedicated dogs.