Evaluation of the aqueous extract of Tridax procumbens Linn. in the healing of full thickness skin wounds in rabbits

To evaluate the wound-healing potential of the aqueous extract of Tridax procumbens Linn., an experimental study was carried out on 12 adult healthy New Zealand white rabbits of 6–8 months age. Two full-thickness excisional skin wounds were surgically created on the back of each animal under anaesthesia. Thereafter, the experimental animals were divided into two groups and treated with topical application of 10% aqueous extract of Tridax procumbens (TP) in the test group and with the normal saline (NS) in control group. The wound-healing was evaluated on the basis of clinicophysiological, haematobiochemical, histopathological and histochemical observations. Significantly faster appearance of granulation tissue, greater wound-contraction along with early healing was seen in the TP-treated group. It was concluded that Tridax procumbens augments wound healing activity in excisional wounds in rabbits.