Hemodynamic and hematobiochemical evaluation of dexmedetomidine, xylazine and triflupromazine as pre-anaesthetics to propofol-isoflurane anaesthesia for various surgeries in dogs

The study was conducted on 18 dogs presented to TVCC, Bidar. The animals were randomly divided into three groups of six animals each. After atropine administration (0.045mg/kg) intramuscularly, the dogs in Group-I received dexmedetomidine (10μg/kg) intravenously, Group-II, xylazine (1mg/kg) and Group-III, triflupromazine (1mg/kg) intravenously. Ten min later anesthesia was induced by propofol (3mg/kg) intravenously and maintained by isoflurane in all the groups. Anaesthetic combinations were evaluated on the basis of hematobiochemical and hemodynamic observations. Haematological, haemodynamic and biochemical parameters did not vary significantly in the three groups, indicating safety of the combinations.