Indian Journal of Veterinary Surgery
  • Year: 2018
  • Volume: 39
  • Issue: 1

Clinicophysiological, haemodynamic and haematological evaluation of different doses of vecuronium bromide in buffaloes

  • Author:
  • Rohit Kumar1,, P. Kinjavdekar2, Deepesh Gautam3, Amarpal4, H.P. Aithal5, A.M. Pawde2, T.B. Sivanarayanan3, D.N. Madhu3, S.K. Patra3
  • Total Page Count: 3
  • Page Number: 43 to 45

1Scientist, Division of Surgery, Indian Veterinary Research Institute, Shivajinagar, Pune-411005 (MH)

2Principal Scientist, Division of Surgery, Indian Veterinary Research Institute, Shivajinagar, Pune-411005, MH

3PG scholar, Division of Surgery, Indian Veterinary Research Institute, Shivajinagar, Pune-411005 (MH)

4Principal Scientist and Head, Division of Surgery, Indian Veterinary Research Institute, Shivajinagar, Pune-411005 (MH)

5Principal Scientist, Training and Education Centre, Indian Veterinary Research Institute, Shivajinagar, Pune-411005 (MH)

Indian Veterinary Research Institute, Izatnagar, Uttar Pradesh, 243122, India

*Corresponding author; E-mail: drrohits.singh@gmail.com

Online published on 19 February, 2019.

Abstract

Vecuronium bromide was administered intravenously in 4 buffaloes of 3–3.5 yr of age weighing 250–300 kg at the dose rate of 40, 50 and 60 μg/kg b.wt (groups A, B and C, respectively) with a minimum gap of 10 days between the trials. Excellent muscle relaxation was recorded in groups B and C up to 15 min. Different physiological, haemodynamic and haematological parameters were within acceptable range in groups A and B. It was concluded that vecuronium bromide (50 μg/kg b.wt) provides adequate muscle relaxation without physiological, haemodynamic and haematological instability and found to be safe for use without assisted ventilation.

Keywords

Buffaloes, Muscle relaxant, Vecuronium bromide