1Ph.D. scholar, Department of Surgery and Radiology, College of Veterinary and Animal Sciences, GBPUAT, Pantnagar-263145, Udham Singh Nagar, Uttarakhand, India
2Professor and Head, Department of Surgery and Radiology, College of Veterinary and Animal Sciences, GBPUAT, Pantnagar-263145, Udham Singh Nagar, Uttarakhand, India
3Assistant Professor, Department of Surgery and Radiology, College of Veterinary and Animal Sciences, GBPUAT, Pantnagar-263145, Udham Singh Nagar, Uttarakhand, India
4Professor, Department of Surgery and Radiology, College of Veterinary and Animal Sciences, GBPUAT, Pantnagar-263145, Udham Singh Nagar, Uttarakhand, India
Gobind Ballabh Pant University of Agriculture and Technology
*Corresponding author; E-mail: drjadonns12@rediffmail.com
Online published on 2 May, 2019.
The study was conducted on 12 adult dogs divided into two groups to study clinicophysiological and haematobiochemical effects of two doses of dexmedetomidine with ketamine and sevoflurane anaesthesia. In group I, atropine sulphate (0.04 mg/kg body wt, s.c.) + dexmedetomidine (10 μg/kg body wt, i.v.) and in group II, atropine sulphate (0.04 mg/kg body wt, s.c.) + dexmedetomidine (15 μg/kg body wt, i.v.) were administered. Anaesthesia was induced with ketamine administered i.v. till effect and maintained with sevoflurane. Duration of anaesthesia, sternal recumbency time, standing time and percent reduction in MAC of sevoflurane were significantly (P<0.05) higher in group II. Significant (P<0.01) but transient changes were recorded in physiological and haematobiochemical parameters in both groups which returned to base line values by the end of study period. Both anaesthetic combinations can be used in canine patients.
Anaesthesia, Dexmedetomidine, Dog, Ketamine, Sevoflurane
