Indian Journal of Veterinary Surgery

  • Year: 2019
  • Volume: 40
  • Issue: 1

Evaluation of halothane, isoflurane and sevoflurane in dogs premedicated with glycopyrrolate-xylazine and anaesthetised with ketamine-diazepam: clinical and haemodynamic study

  • Author:
  • H.P.S. Gangwar1, S. Purohit2,, R.K. Vijay1, R.P. Pandey3
  • Total Page Count: 5
  • DOI:
  • Page Number: 34 to 38

1MVSc scholar, Department of Veterinary Surgery and Radiology, College of Veterinary Science and Animal Husbandry

UP Pandit Deen Dayal Upadhayaya Pashu-Chikitsa Vigyan Vishwavidyalaya Evam Go-Anusandhan Sansthan (DUVASU), Mathura-281001, Uttar Pradesh, India

2Associate Professor, Department of Veterinary Surgery and Radiology, College of Veterinary Science and Animal Husbandry

3Professor and Head, Department of Veterinary Surgery and Radiology, College of Veterinary Science and Animal Husbandry

Abstract

The clinical study was conducted on 18 dogs to evaluate halothane, isoflurane and sevoflurane inhalant anaesthetic agents for maintenance of general anaesthesia. The dogs were randomly divided into three equal groups, A, B and C. All the animals of three groups received glycopyrrolate (0.01 mg/kg b.wt) and xylazine (0.5 mg/kg b.wt) as preanaesthetics administered intramuscularly with 10 min interval between the drugs. After 10 min of administration of preanaesthetics, anaesthesia was induced by diazepam (0.25 mg/kg b.wt) and ketamine (5.0 mg/kg b.wt) administered intravenously. After complete induction, endotracheal intubation was done, and the animal was connected to an anaesthetic machine, and anaesthesia was maintained with halothane, isoflurane or sevoflurane in 100% oxygen in groups A, B and C, respectively. The results indicated faster recovery in sevoflurane group, while maintenance cost was lowest in halothane group.

Keywords

Diazepam, Dogs, Glycopyrrolate, Halothane, Isoflurane, Ketamine, Sevoflurane, Xylazine