Evaluation of ketamine and ketofol anaesthesia in atropine-dexmedetomidine-butorphanol premedicated dogs undergoing elective ovariohysterectomy

Twelve healthy female dogs premedicated with atropine-dexmedetomidine and butorphanol for elective ovariohysterectomy were randomized for administration of ketamine (group A) and ketofol 1:1 (group B) at the dose rate of 300 µg/kg body weight per minute for induction and maintenance of anaesthesia. Physiological and haemodynamic observations were recorded at 0 min and at 15, 20, 30, 45, 60, 75, 90, 105, 120 min. Dose of induction in group B (3.7±1.57 mg/kg) was lower than group A (5.47±1.02 mg/kg), and quality of recovery was smooth in group B than group A. It was concluded that ketofol 1:1 was better than ketamine alone for maintenance of anaesthesia using constant rate of infusion in dogs.