1MVSc Scholar, Division of Veterinary Surgery & Radiology, Sher-e Kashmir University of Agricultural Sciences and Technology of Kashmir, Srinagar, Kashmir-190 006
2Professor, Division of Veterinary Clinical Complex, Sher-e Kashmir University of Agricultural Sciences and Technology of Kashmir, Srinagar, Kashmir-190 006
3PG Scholar, Division of Veterinary Clinical Complex, Sher-e Kashmir University of Agricultural Sciences and Technology of Kashmir, Srinagar, Kashmir-190 006
4Assistant Professor, Division of Veterinary Clinical Complex, Sher-e Kashmir University of Agricultural Sciences and Technology of Kashmir, Srinagar, Kashmir-190 006
5Professor, Division of Veterinary Microbiology and Immunology, Faculty of Veterinary Sciences and Animal HusbandrySher-e Kashmir University of Agricultural Sciences and Technology of Kashmir, Srinagar, Kashmir-190 006
Sher-e Kashmir University of Agricultural Sciences and Technology of Kashmir, Srinagar, Kashmir-190 006
*Corresponding author; E-mail: fazili_mr@yahoo.co.in
Online Published on 14 September, 2022.
Objective of the present study was to evaluate Regional Limb Perfusion (RLP) of ampicillin-sulbactam for acute foot infections in sheep. Adult sheep (n=24) of either sex (18F and 6M) reported for treatment of acute single foot affection were included. Majority of the animals had involvement of forelimbs (75%), right side feet (62.5%) and lateral claws (58.3%). Lesions were found in coronary, interdigital, heel and sole areas. Local signs included pastern swelling, hyperaemia, alopecia, overgrown hooves, moist/discharging and contaminated wounds. All the animals were provided local wound management for seven days and analgesia (nimesulide, 2.0 mg/kg body wt, i.m.) daily for three days. Animals of group T1 (n=8) were given ampicillin-sulbactam 2.5 mg/kg body wt, 3.0 mL, OD for three days as RLP. Group T2 (n=8) sheep received ampicillin-sulbactam 10.0 mg/kg body wt, 3.0 mL i.v., OD for three days. Sheep belonging to group T3 (n=8) received no antibiotic. Lameness subsided and foot lesions showed substantial improvement within three days in all sheep except five sheep from group T3. From this study, it can be concluded that in sheep with foot infections, RLP is a simple, economical and field applicable alternate technique of antibiotic administration; and ampicillin-sulbactam 2.5 mg/kg body wt as RLP is as effective as 10.0 mg/kg body wt by intravenous route.
Ampicillin-sulbactam, Foot infections, Nimesulide, Regional Limb Perfusion, Sheep
