Indian Journal of Veterinary Surgery
  • Year: 2021
  • Volume: 42
  • Issue: 1

Clinicophysiological and hematobiochemical evaluation of propofol and etomidate as anaesthetic induction agents in diazepam premedicated dogs

  • Author:
  • Mansi1, Adarsh Kumar2,*, Amit Kumar3, Sukti Naryal4, S.P. Tyagi5
  • Total Page Count: 4
  • Page Number: 48 to 51

1MVSc Scholar, Department of Surgery and Radiology, Dr G.C. Negi College of Veterinary and Animal Sciences, CSK Himachal Pradesh Krishi Vishvavidyalaya, Palampur-176 062 (Himachal Pradesh)

2Professor and Head, Department of Surgery and Radiology, Dr G.C. Negi College of Veterinary and Animal Sciences, CSK Himachal Pradesh Krishi Vishvavidyalaya, Palampur-176 062 (Himachal Pradesh)

3Assistant Professor, Department of Surgery and Radiology, Dr G.C. Negi College of Veterinary and Animal Sciences, CSK Himachal Pradesh Krishi Vishvavidyalaya, Palampur-176 062 (Himachal Pradesh)

4MVSc Scholar, Department of Surgery and Radiology, Dr G.C. Negi College of Veterinary and Animal Sciences, CSK Himachal Pradesh Krishi Vishvavidyalaya, Palampur-176 062 (Himachal Pradesh)

5Professor, Department of Surgery and Radiology, Dr G.C. Negi College of Veterinary and Animal Sciences, CSK Himachal Pradesh Krishi Vishvavidyalaya, Palampur-176 062 (Himachal Pradesh)

CSK Himachal Pradesh Krishi Vishvavidyalaya, Palampur-176 062 (Himachal Pradesh)

*Corresponding author; E-mail: adarsh9kan@gmail.com

Online Published on 14 September, 2022.

Abstract

Thirty client-owned dogs of either sex, divided into 2 equal groups were used to evaluate the effects of propofol (group P) and etomidate (group E) as an induction agents. All the dogs were premedicated with butorphanol (0.2 mg/kg body wt, i.m.), atropine sulphate (0.04 mg/kg body wt, s.c.) and diazepam (0.5 mg/kg body wt, i.v.). Induction of anaesthesia was done by propofol in group P and etomidate in group E given intravenously to effect. All the dogs were maintained on isoflurane mixed with 100% oxygen throughout the period of surgery. The mean induction dose of propofol and etomidate was 3.38±0.16 and 1.22±0.105 mg/kg body wt, respectively. The quality of anaesthetic induction was smooth with propofol as compared to etimidate. Transient changes were recorded in clinico-physiological and haemato-biochemical parameters in both the groups. Quality of recovery was comparatively better with etimidate than propofol. Etomidate was superior over propofol in maintaining the cardiovascular and haemodynamic stability.

Keywords

Dog, Propofol, Etomidate, Diazepam