Indian Journal of Veterinary Surgery
  • Year: 2023
  • Volume: 44
  • Issue: 1

Clinical evaluation of mesenchymal stem cell conditioned media (MSC-CM) for the treatment of wounds in dog

1PhD Student, Department of Surgery and Radiology, Mumbai Veterinary College, Mumbai, Maharashtra Animal and Fishery Sciences University, Nagpur (Maharashtra)

2Professor and Head, Department of Surgery and Radiology, Mumbai Veterinary College, Mumbai, Maharashtra Animal and Fishery Sciences University, Nagpur (Maharashtra)

3Professor and Head, Department of Animal Reproduction and Gynaecology, PGIVAS, Akola, Maharashtra Animal and Fishery Sciences University, Nagpur (Maharashtra)

4Veterinary Officer, BMC, Mumbai, Maharashtra Animal and Fishery Sciences University, Nagpur (Maharashtra)

5Assistant Professor, Department of Surgery and Radiology, Mumbai Veterinary College, Mumbai, Maharashtra Animal and Fishery Sciences University, Nagpur (Maharashtra)

*Corresponding author; E-mail: drsuraut@gmail.com

Online published on 4 June, 2025.

Abstract

The study was done to evaluate the effect of mesenchymal stem cell conditioned media (MSC-CM) on healing of cutaneous wounds in dogs. Twelve clinical cases of dogs were used in the study in two groups. Group I animals acted as control and group II animals were treated by smearing the wound with MSC-CM. The measurements of wound area were taken before the start of treatment and on every fourth day till healing of the wound. The results showed that the wounds of MSC-CM treated group healed earlier as compared to the control group, indicating that the MSC-CM helped to accelerate the wound healing, without causing any harmful effect.

Keywords

Dog, Mesenchymal stem cell conditioned media, Wound healing