1MVSc Scholar, Department of Veterinary Surgery and Radiology, College of Veterinary Science and Animal Husbandry, Acharya Narendra Deva University of Agriculture and Technology, Kumarganj, Ayodhya (UP)-224 229
2Professor and Head, Department of Veterinary Surgery and Radiology, College of Veterinary Science and Animal Husbandry, Acharya Narendra Deva University of Agriculture and Technology, Kumarganj, Ayodhya (UP)-224 229
3Assistant Professor, Department of Veterinary Surgery and Radiology, College of Veterinary Science and Animal Husbandry, Acharya Narendra Deva University of Agriculture and Technology, Kumarganj, Ayodhya (UP)-224 229
4Assistant Professor, Department of Veterinary Clinical Complex, College of Veterinary Science and Animal Husbandry, Acharya Narendra Deva University of Agriculture and Technology, Kumarganj, Ayodhya (UP)-224 229
*Corresponding author; E-mail: dranilvet2007@gmail.com
Online published on 16 June, 2025.
In the present study, glutaraldehyde-cross linked bubaline acellular periosteum (GBAP) scaffolds were used to augment long bone fracture healing in dogs. Twelve client-owned male dogs, aged 6-9 yr, with fracture of long bones, were divided randomly into groups A (control) and B (treatment). The fracture was stabilized by intramedullary pinning in both groups. Further, in group B animals, GBAP scaffold was placed circumferentially covering the fractured site. The functional limb usage, callus index, serum calcium, phosphorus, alkaline phosphatase, oxidant and antioxidant status of the patients were evaluated. By day 45, group B animals showed full function at standing and walking, and mineralization of bone at the fracture site. The serum calcium, inorganic phosphorus and alkaline phosphatase levels were higher in treatment group. Levels of MDA, GSH and catalase increased significantly in control group. It was concluded that GBAP scaffolds helped to augment fracture healing and reduce the healing time.
Acellular periosteum, Bone scaffold, Dog, Fracture healing
