Indian Journal of Veterinary Surgery
  • Year: 2024
  • Volume: 45
  • Issue: 2

Anaesthetic efficacy of xylazine-ketamine-butorphanol and dexmedetomidine-ketamine-butorphanol combination for ovariohysterectomy in cat

  • Author:
  • S.S. Khandare1, M.G. Thorat2,*, R.V. Raulkar3, F.A. Fani3, S.G. Deshmukh3, A.D. Chopade1, A.K. Jami1
  • Total Page Count: 5
  • Page Number: 109 to 113

1MVSc Scholars, Department of Surgery and Radiology, Post Graduate Institute of Veterinary and Animal Sciences (PGIVAS), Maharashtra Animal and Fishery Sciences University, Akola- 444 104, (Maharashtra)

2Professor and Head, Department of Surgery and Radiology, Post Graduate Institute of Veterinary and Animal Sciences (PGIVAS), Maharashtra Animal and Fishery Sciences University, Akola- 444 104

3Assistant Professor, Department of Surgery and Radiology, Post Graduate Institute of Veterinary and Animal Sciences (PGIVAS), Maharashtra Animal and Fishery Sciences University, Akola- 444 104

*Corresponding author; E-mail: milindthrt@yahoo.co.in

Online published on 13 October, 2025.

Abstract

The study was conducted to compare the anaesthetic efficacy of xylazine-ketamine-butorphanol and dexmedetomidine-ketaminebutorphanol combinations for ovariohysterectomy in cats. Twelve healthy cats brought for ovariohysterectomy were randomly divided in two groups, in one group dexmedetomidine-ketaminebutorphanol and in another group xylazine-ketamine-butorphanol were used to induce anaesthesia. The animals were assessed based on different clinical, physiological and biochemical parameters recorded before induction, at induction and after recovery from anaesthesia. The cats administered with dexmedetomidineketamine-butorphanol combination exhibited a better quality of anaesthesia, a shorter induction time and recovery time. A significant variation was observed in clinico-physiological parameters after anaesthetic induction in both the combinations. A non-significant variation in the values of haematological and biochemical parameters was observed in both groups for the duration of anaesthesia. It can be concluded that the combination of dexmedetomidine-ketamine-butorphanol offered superior anaesthetic quality with smooth induction and faster recovery for ovariohysterectomy in cats, compared to the use of xylazineketamine-butorphanol.

Keywords

Anaesthesia, Cat, Dexmedetomidine, Ovariohysterectomy