Indian Journal of Veterinary Surgery
  • Year: 2024
  • Volume: 45
  • Issue: 2

Electrocardiography study in the dogs subjected to ovariohysterectomies anaesthetized with tiletamine-zolazepam and ketamine-diazepam combinations

1MVSc Scholar, Department of Veterinary Medicine, Post Graduate Institute of Veterinary and Animal Sciences, Akola, Maharastra Animal and Fishery Science University, Nagpur-440001 (MS)

2Professor & Head, Department of Veterinary Medicine, Post Graduate Institute of Veterinary and Animal Sciences, Akola, Maharastra Animal and Fishery Science University, Nagpur-440001 (MS)

3Assistant Professor, Department of Veterinary Surgery and Radiology, Post Graduate Institute of Veterinary and Animal Sciences, Akola, Maharastra Animal and Fishery Science University, Nagpur-440001 (MS)

4Ph.D. Scholar, Department of Veterinary Medicine, Post Graduate Institute of Veterinary and Animal Sciences, Akola, Maharastra Animal and Fishery Science University, Nagpur-440001 (MS)

*Corresponding author; E-mail: milindthrt@yahoo.co.in

Online published on 13 October, 2025.

Abstract

The study was conducted to evaluate the electrocardiographic changes in 12 healthy female dogs undergoing ovariohysterectomy pre-anaesthetized with xylazine. These dogs were randomly divided into two equal groups. In Group I induction and maintenance of anaesthesia was achieved using Tiletamine – Zolazepam (3 mg/kg BW IV) combination whereas in Group II induction and maintenance of anaesthesia was achieved using Ketamine (3 mg/kg BW IV) preceded by administration of Diazepam (0.25 mg/kg BW IV). Significant increase in the value of P wave duration was observed at 30 min. P-R and Q-T interval was significantly increased at different time intervals. Amplitude of T wave was increased in both groups. Sinus arrhythmia and sinus bradycardia were recorded in both groups, however, first degree AV block was observed in Group I.

Keywords

Dogs, ECG, Anaesthesia, Xylazine