INROADS- An International Journal of Jaipur National University
  • Year: 2014
  • Volume: 3
  • Issue: 2

Recombinant Insulin: A Boon to Medical Sciences

1Ph. D Scholar, School of Life Sciences, Jaipur National University, Jaipur, Rajasthan, India

2Associate Professor, School of Life Sciences, Jaipur National University, Jaipur, Rajasthan, India

*Corresponding author E-mail id: alefiya7bohra@gmail.com

Online published on 8 October, 2015.

Abstract

Insulin is a 5808 Da polypeptide hormone produced in the pancreas by Islets of Langerhans. This hormone is involved in the regulation of blood glucose level and in the metabolism of carbohydrates, fats, and starch. It consists of two polypeptide chains. A chain composed of 21 amino acids and B chain containing 30 amino acids. Insulin extracted from animal pancreas especially Bovine insulin, has been previously used by diabetic patients to full fill their requirements. However this has now been partly replaced by recombinant human insulin. This recombinant product was first developed by Genentech and Marketed by Eily Lily as HUMULIN. The recombinant product is identical to that produced by human body. Recombinant insulin is now available from either Escherichia coli or Saccharomyces cereviceae.

Keywords

Recombinant Insulin, Saccharomyces cereviceae, Diabetes, Humulin, Insulin sniffs, Insulin pills