Paraganglioma Retroperitoneum a rare Neuroendocrine Tumour: Experience of Five Cases

Paragangliomas are rare neuroendocrine tumours arising from a widely dispersed collection of specialized neural crest cells (Feng et al., 2009). The adrenal medulla represent the largest collection of paraganglionic tissue; tumours derived from them occur much more frequently than in extra-adrenal locations. It has been estimated that 10% of paragangliomas arise outside the adrenal glands (Wen et al., 2010). The most common site of extra-adrenal occurrence is intra-abdominal, usually within para-aortic region.