1College of Veterinary Science and AH, Orissa University of Agriculture and Technology, Bhubaneswar
2Centre for Wildlife
3Central Institute on Research for Goat, Makhdoom, Mathura
Environmental Medicine Laboratory, Division of Medicine, Indian Veterinary Research Institute, Izatnagar, Bareilly - 243122 (Uttar Pradesh)
*Corresponding Author E-mail: dramitrajgupta@gmail.com
Online published on 19 March, 2013.
Urinary hydroxyproline an index for bone metabolism was determined in cattle from fluoride endemic area. Cattle (n=12) were divided in two equal groups of six animals each. Group I and II served as healthy and disease control, respectively. Urine samples were collected from both groups for estimation of hydroxyproline. Significantly (P<0.05) higher concentration of hydroxyproline was found in cattle from fluoride endemic area as compared to healthy animals. The study suggested hydroxyproline levels in urine can be assessed as a non-invasive biomarker for diagnosing osteofluorosis in animals residing in fluorotic area.
Cattle, fluorosis, hydroxyproline
