Therapeutic Management of Mastitis in Caprines

The present investigation was undertaken to evaluate the comparative therapeutic efficacy of Ceftriaxone-Tazobactum and Amoxicillin-Dicloxacillin for management of caprine clinical mastitis. Mastitic quarters of goats were diagnosed to be associated with Staphylococcus spp., Streptococcus spp., E.coli and Klebsiella infection. The organisms showed highest sensititvity to Ceftriaxone followed by Amoxy-Clav, Enrofloxacin, Gentamicin, whereas, all isolates were resistant to Penicillin G. The clinical and bacteriological cure rates obtained in the present study were found to be 100 percent in both groups. The response was excellent in animals treated with Ceftriaxone-Tazobactum @ 10 mg/kg b.wt as there was marked relief of symptoms by second day of treatment itself. Goats treated with Amoxicillin-Dicloxacillin @ 10 mg/kg b.wt responded slowly. Mild relief was noticed on second day but marked effect was evident third day onwards. Both groups were given supportive treatment with Flunixin meglumine. Isolation studies were conducted again on 5^th day after recovery in both groups and all samples were found to be culturally negative.