Therapeutic Management of Idiopathic Dilated Cardiomyopathy Concurrent with Diabetic Ketosis in a Dog

A male Rottweiler dog was presented with complaint of thick purulent bilateral nasal and lachrimal discharge, polyuria, polydipsia and wound on ventral thoracic region and on left hind paw since last two months. Physical examination revealed depression, abdominal fluid thrill and pale conjuctival mucus membrane. Cardiac auscultation revealed systolic murmur, pulse deficit and irregular pulse. Electrocardiography revealed sinus arrhythmia with atrial fibrillation. Radiology of heart revealed dilated cardiomyopathy which was supported by echocardiographic findings. Hematology was indicative of monocytopenia with neutrophilia. Serum biochemistry revealed marked increase in fasting glucose and cardiac specific enzyme levels. Urinalysis revealed marked glucosuria and ketonuria. Serum oxidant-antioxidant status revealed decreased levels of antioxidants compared to healthy control. On the basis of clinical signs, serum biochemistry, urinalysis, radiology and echocardiography, a confirmative diagnosis of diabetic ketosis concurrent with dilated cardiomyopathy was made. The dog was treated with medications and improvement was observed by thirty days post-therapy. The case was monitored monthly for six months.