1Assistant Director, Department of Animal Husbandry and Veterinary Services
2Retired Professor and Head, Department of Animal Husbandry and Veterinary Services
3Assistant Professor, Department of Animal Husbandry and Veterinary Services
Department of Veterinary Parasitology, Veterinary College, Karnataka Veterinary Animal and Fisheries Sciences University (KVAFSU), Hebbal, Bengaluru - 560024 (Karnataka)
*Corresponding author, E-mail: dhanu.hanumappa@gmail.com
Online published on 1 October, 2020.
The study evaluates efficacy of Fenbendazole and Ivermectin against horse strongyles using in vitro techniques. The in-vitro egg hatch assay (EHA) revealed ED50 value of 0.1328±0.0216 μg/ml and LD50 LCL-UCL of 0.0793-0.1953 μg/ml for Fenbendazole. LD50 value was higher than 0.1μg/ml indicating presence of resistance to Fenbendazole in farm horses. Larval development test (LDA) of strongyle eggs with Fenbendazole and Ivermectin showed LD50 values of 0.127±0.0191μg/ ml (LD50 LCL-0.085μg/ml and LD50 UCL-0.177 μg/ml) and LD50 values of 0.0012±0.0002 μg/ml (LD50 LCL-0.0008 μg/ml and LD50 UCL-0.0018 μg/ml) respectively. It was concluded that strongyles had developed resistance to Fenbendazole and Ivermectin was fairly effective.
Equine, Fenbendazole, Ivermectin, Strongyle
