1Department of Anatomy, Faculty of Medicine, Zahedan University of Medical Sciences and Health Services, P.O. Box 98165-493, Zahedan, Iran.
2Department of Physiology, Faculty of Science, Sistan and Baluchestan University, Zahedan, Iran.
3Department of Biology, Faculty of Science, Sistan and Baluchestan University, Zahedan, Iran.
*Corresponding author: Tel: +98-541-2423838, Fax: +98-541-2415082, Mob: +98-9153414354, E-mail: mr_arabz@yahoo.com
To examine the structural and histochemical changes of aorta and common carotid arteries in male diabetic rats, 63 male Sprague Dawley rats were randomly divided into experimental (n=36) and control (n=27) groups. Diabetes was induced by intraperitoneal injection of 60 mg/kg of streptozotocin in experimental group. There was a significant difference only for periodic acid schiff positive material in subintimal connective tissue between control and 4 months diabetic groups (P<0.007). Peanut agglutinin staining showed the presence of Galactose/N-Acetyl galactosamine in glycoconjugates of sub-endothelial and adventitial components of studied arteries. It seems that in diabetes, the rate of glycosylation of cell surface and extracellular matrix glycoconjugates changed slowly.
Aorta, carotid, diabetes mellitus, lectin, rat
