Journal of Applied Animal Research
  • Year: 2010
  • Volume: 37
  • Issue: 2

Immune Response of Rats to Peste Des Petit Ruminant (PPR) Vaccination

  • Author:
  • M.C.O. Ezeibe1,, J.I. Eze1, N.M. Ukomadu3, O.S. Chukwu1, I.C. Eze2, O.N. Okoroafor1, J.A.C. Ugonabo2, A.A. Ngene1, M.E. Sanda1, O. Ijabo1
  • Total Page Count: 2
  • Page Number: 239 to 240

1Department of Veterinary Medicine, University of Nigeria, Nsukka, Nigeria.

2Department of Microbiology, University of Nigeria, Nsukka, Nigeria.

3Department of Veterinary Parasitology and Entomology, University of Nigeria, Nsukka, Nigeria.

*For correspondence: E-mail: maduikeezeibe@yahoo.com.

Abstract

Rats were used as animal models to study immune response to vaccination with pestes des petit ruminants (PPR) monospecific vaccine. One group (10 rats) was vaccinated with PPR vaccine (Nigeria 75/1). The second group (10 rats) served as unvaccinated control. Two weeks post vaccination, haemagglutinationinhibition (HI) test was done. The vaccinated group had higher HI titre of 6617±653 suggesting that the rats could be used for assessment of immune response to PPR vaccine.

Keywords

PPR vaccine, haemagglutination-inhibition test, small ruminants