1Poostchi Eye Research Center, Department of Ophthalmology, Shiraz University of Medical Sciences, Shiraz, Iran.
2Neuroscience Research Center, Department of Neurosurgery, Shiraz University of Medical Sciences, Shiraz, Iran.
3Stem Cell and Transgenic Technology Research Center, Department of Pharmacology, Shiraz University of Medical Sciences, Shiraz, Iran.
4Gastroenterohepatology Research Center, Department of Pathology, Shiraz University of Medical Sciences, Shiraz, Iran.
*For correspondence: Tel: #98-711-6474263; Fax: #98-711-6474263; E-mail: mehrabad@sums.ac.ir
To evaluate correlation between intraocular pressure (IOP) and intracranial pressure (ICP) 15 mature dogs were divided into three equal groups. Under general anesthesia, the IOP and ICP were determined. Group 1 received timolol, group 2 latanoprost and group 3 underwent trabeculotomy in a single eye. After 2 and 4 weeks, the IOP and ICP were measured again. Before any drug administrations or surgery, the correlation between primary IOP and primary ICP was not significant (P>0.05) but after 2 and 4 weeks, there was a considerable negative linear correlation between these two measures (r= - 0.595; P=0.01) and (r=- 0.570; P=0.02), respectively. There was a negative linear correlation between IOP and ICP (r=-0.67; P=0.001) when the multiple regression formula was applied to make a model.
Intraocular pressure, intracranial pressure, correlation, dog
