1Department of Biotechnology, Vinayaka Mission’s Kirupananda Variyar Engineering College, Vinayaka Mission’s Research Foundation, Salem, India
10University Centre for Research and Development, Chandigarh University, Mohali, India
11Department of Microbiology, Akal College of Basic Sciences, Eternal University, Baru Sahib, Sirmour, India
12Department of Genetics, Plant Breeding and Biotechnology, Dr. Khem Singh Gill Akal College of Agriculture, Eternal University, Baru Sahib, Sirmour, India
2Department of Environmental Science, SP College, Srinagar, India
3Department of Pharmaceutical Engineering, Vinayaka Mission’s Kirupananda Variyar Engineering College, Vinayaka Mission’s Research Foundation, Salem, India
4School of Allied Health Sciences, VIMS Hospital Campus, Vinayaka Mission’s Research Foundation, Salem, India
5Department of Environmental Science, GDC Eidgahs, Srinagar, India
6Centre for Research Impact and Outcome, Chitkara University Institute of Engineering and Technology, Chitkara University, Rajpura, India
7Chitkara Center for Research and Development, Chitkara University, Baddi, India
8Department of Biochemistry, Dr. Ram Manohar Lohia Avadh University, Ayodhya, India
9Department of Food Technology, School of Applied and Life sciences, Uttaranchal University, Dehradun, India
*Corresponding Authors Rangasamy Kirubakaran, Department of Biotechnology, Vinayaka Mission’s Kirupananda Variyar Engineering College, Vinayaka Mission’s Research Foundation, Salem, India, Email: rangasamykirubakaran@gmail.com
**Ajar Nath Yadav, Department of Genetics, Plant Breeding and Biotechnology, Dr. Khem Singh Gill Akal College of Agriculture, Eternal University, Baru Sahib, Sirmaur, India, Email: ajarbiotech@gmail.com
Online published on 06 December, 2025.
The need for chemical-free farming methods is becoming more important due to the detrimental impacts of chemicals on human health and the environment. Finding innovative ways for the establishment of sustainable agricultural is crucial that may avoid the overuse of chemical fertilizers and pesticides as a means of increasing output. Microorganisms that promote plant development and act as biocontrol agents have become safe substitutes for chemical fertilizers in the agriculture sector. Endophytic microorganisms or microorganisms associated with plants, have become a vital and promising tool for sustainable agriculture. Endophytic Streptomyces act as the alternative for preventing disease-causing microorganisms and help to regulate plant growth. Bacteria belonging to the genus Streptomyces are well-known producers of secondary metabolites, which can be potentially utilized to replace chemical fertilizers and pesticides. The current status of endophytic Streptomyces in sustainable agriculture is employed as safe biocontrol and plant growth-promoting (PGP). This review emphasizes the biocontrol and PGP benefits of the endophytic Streptomyces. Additionally, their ability to enhance plant growth has been confirmed in a number of crops, thus encouraging the wide use of streptomycetes as biofertilizers to increase plant productivity.
Biofertilizers, Biocontrol, Bioformulation, Endophytes, Streptomyces
