1Division of Animal Genetics, ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly, Uttar Pradesh, India
2Joint Director (Academic) Deemed University, ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly, Uttar Pradesh, India
*Corresponding author: B Bhushan; E-mail: bhushan.drbharat@gmail.com
Online Published on 21 September, 2022.
Bovine mastitis has for a long period severely restrained production performance in the dairy enterprise. Despite improved management approaches and veterinary services, mastitis is still responsible for a major loss of the economy to the extent of worldwide. Genetic control as in development of protective immune mechanism and disease tolerant animal is considered an economic and prophylactic technique for health improvement management. We, therefore, need to recognise thoroughly the factors regulating the association between both the etiological agents and the host’s mammary gland cells. Consequently, we need to determine differentially expressed genes during particular conditions in regard to mastitis. High-throughput transcriptome sequencing technique (RNA-Seq) has evolved as the main option for the analysis of differential gene expression setting the foundations for modern genetic research.
• Mastitis in bovine is among the highly prevalent and devastating disease condition globally.
• RNA-Seq is a preferred tool to map and quantify transcriptome profile.
• To unfold the underlying functional elements of the genome entirely and their inter-relationship with the mastitis.
Mastitis, Disease resistance, RNA sequencing, Gene expression
