1Veterinary Assistant Surgeon, AH Department, Andhra Pradesh, India
2Assistant Professor, Sri Venkateswara Veterinary University, Tirupati
3Professor and University Head, Sri Venkateswara Veterinary University, Tirupati
Department of Veterinary Microbiology, NTR College of Veterinary Science, Sri Venkateswara Veterinary University, Gannavaram, Andhra Pradesh, India
*Corresponding author: V Govind; E-mail: govindvet@gmail.com
Online Published on 14 July, 2023.
Ranikhet disease (RD) is important infectious disease of chicken. Although vaccination available, sometimes immunosupression induced by factors like stress lead to vaccination failures. Immunostimulation by using of herbs in Ayurveda for enhancing the general host immune status is well documented. Present study is aimed to investigate the immunostimulatory effect of important Indian herbs Guduchi (Tinospora cordifolia) and Shatavari (Asparagus racemosus) on RD vaccination in chickens. Stem dry powder of Guduchi and root dry powder of Shatavari were mixed in regular poultry feed to different groups of birds. All the groups of birds were vaccinated with primary, 1st booster and 2nd booster doses of RD vaccine and the sera samples were tested for antibody levels by hemagglutination inhibition (HI) test. Significant higher (p < 0.001) HI antibody titers were found in Shatavari supplemented group and in both the herbs supplemented groups of chickens after 1st and 2nd booster doses of RD vaccination in comparison to RD vaccinated control group. However, Guduchi didn’t show any significant immunostimulating properties on RD vaccination after 1st booster and 2nd booster doses of vaccination.
• Supplementing the root powder of Indian herb Shatavari in layers had resulted in significant increase antibody titre in response to RD vaccination.
• Guduchi stem power supplementation has low response in immune stimulating properties against RD vaccination in layers.
Layers, Guduchi, Immunomodulation, Shatavari, Vaccination failure
